Recombinant Human Insulin-Like Growth Factor IGF-1

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Zhuhai Gene Biocon Biological Technology Co., Ltd.

Business Type:Manufacturer

Country/Region:China

Ddu Verified

HOT Rank

8/10

Product Information

  • Active Ingredients:Human Insulin-Like Growth Factor
  • Molecular Weight:7.7kD
  • Assay:≥95%
  • Pharmacopeia:CP
  • Package Type:1mg/vial; 10mg/vial; 100mg/vial
  • Shelf Life:2 years
  • Storage:-20℃
  • Place of Origin:Zhuhai

Description

Product Description

Insulin-like growth factor-1 (IGF-1), also known as growth factor C (Somatomedin C), belongs to the insulin-like growth factor family and is structurally homologous to proinsulin. IGF-1 is a mitogenic polypeptide growth factor that stimulates the proliferation and survival of various cells such as muscle, bone and cartilage in vitro. 

IGF-1 binds to IGF-1R, IGF-2R and insulin receptors and activates a variety of signaling pathways involved in cell proliferation, differentiation, survival, growth, apoptosis and regeneration. Recombinant human insulin-like growth factor (IGF-1) consists of 70 amino acids and is a biologically active protein for cell culture. 

The product is a lyophilized powder prepared by recombinant yeast, separated and purified by multiple steps, and then freeze-dried.


Product Features

Species: Human.

Source: Pichia pastoris.

Appearances: White or off-white lyophilized powder.

Molecular weight: 7.7kD±0.8 kD.

Purity: ≥95% (SDS-PAGE).

Active: ≥2.2×105 IU/mg pro. (Check COA).

Isoelectric point: 8.4~8.6.

Solubility: Good solubility in water, buffer, and medium.


Biological activity: according to the method of Chp 2020, The biological activity of IGF-1 was measured by stimulating the human breast cancer cell line MCF-7.


Notice and Disclaimer

a. Avoid long-time storage in a high-temperature environment.

b. Avoid contamination during the operation of this product.

c. The product is for research use only and should not be used for diagnosis or treatment of animals or humans. 


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